Molecular mechanism of nur77 gene expression and downstream

nuri77The expression of nur77 gene and Nur77 are induced at 0–4 hr after 10 µM forskolin treatment in PC12 cells. (A) PC12 cells were treated with 10 μM forskolin.nur77Overview of the antiinflammatory snaling pathway of the orphan nuclear receptor Nur77 in EC. LPS induces an increase of Nur77 expression that negatively regulates endothelial